No one dies on this man's watch.

That's how we always felt about Preston Burke, a brilliant heart surgeon and a kind, compassionate person. The consummate professional, and a great cook to boot. What's not to love about Dr. Burke?

Preston grew up in Alabama, where his mother owns a restaurant. He is the chief cardio-thorasic surgeon at Seattle Grace, and was long known for his grace under pressure as well as his incredible scalpel skills. Seriously, you cannot rattle the guy in the operating room or in real life.

Cristina Yang has tried during her romance with the handsome physician, which began during Season One, and which he initially broke off because of concern for his reputation.

The polar opposites then back together, however, and Cristina moved into his apartment. The evolution of their relationship despite their differences was a focal point of Grey's Anatomy for much of its second and third seasons. Preston also warmed up to Derek Shepherd, despite initial friction between the two.At the end of the second season, Preston was shot, leading to an injury that caused a tremor in his hand.

While he was healed as far as the doctors could tell, he felt pressure to return to work before he was ready. Cristina helped conceal his hand tremor, a conspiracy that ultimately boiled over and cost Burke the chance to take over for Richard Webber as Chief of Surgery.

Burke and Cristina got engaged halfway through Season Three, but at the end of the season, he left her at the altar after determining, once and for all, that she did not want to go through with it or be the person he wanted her to be. Preston has left Seattle Grace, never to return.

Preston Burke Quotes

PRESTON: [enters his apartment] "I am Preston Burke. I am a widely renowned cardio-thoracic surgeon. I am a professional and moreover I am a good, kind person. I am a person that cleans up after himself. I am a great cook. And you? You are an unbelievable slob. A slovenly, angry intern. I am Preston Burke. And you... are the most competitive, guarded, stubborn... the most challenging person I have ever met. And I love you. Why the hell won't you just let me?
CRISTINA: "I gave up my apartment 20 minutes ago."
PRESTON: [pauses] "Well, alright then."

PRESTON: "So, I have a question to ask. I checked the schedule and I noticed that both you and I are off tonight. I have a favorite restaurant. I made reservations."
CRISTINA: "None of those were questions."

Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)