Watch Agents of S.H.I.E.L.D. Season 4 Episode 21 online via TV Fanatic with over 7 options to watch the Agents of S.H.I.E.L.D. S4E21 full episode. Affiliates with free and paid streaming include Amazon, iTunes, Vudu, Netflix, YouTube Purchase, Google Play, and Verizon On Demand.
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On Marvel's Agents of S.H.I.E.L.D. Season 4 Episode 21, an even deadlier enemy looms in the aftermath of the team's victory in the Framework.