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Sam vs. Dean - Supernatural Season 10 Episode 23
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"Brother's Keeper"
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Dean makes a shocking decision regarding the Mark of Cain that would change not only his life, but Sam’s too.

Dealing With the Decision - Supernatural
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"The Prisoner"
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On Supernatural Season 10 Episode 22, Sam tries to come to terms with his decision while Dean decides to take matters with the Stynes into his own hands.

Reading Rowena - Supernatural Season 10 Episode 21
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"Dark Dynasty"
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Dean and Sam investigate a bizarre murder and realize the killer bears the same tattoo as those from the Styne family.

Dean and Castiel - Supernatural Season 10 Episode 20
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"Angel Heart"
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How far will Castiel go? That's the main question hovering over Supernatural Season 10 Episode 20.

Dean - Supernatural Season 10 Episode 19
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"The Werther Project"
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Sam learns that former Men of Letters, Magnus, once built a magical box, and Sam sets out to find it in the hopes it can cure Dean of the Mark of Cain.

Removing the Mark of Cain - Supernatural
Watch Supernatural Season 10 Episode 18
"Book of the Damned"
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On Supernatural Season 10 Episode 18, Sam and Dean get a call from Charlie who tells them she found the Book of the Dead that could help remove the Mark of Cain.

Rowena's Tattoos - Supernatural Season 10 Episode 17
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"Inside Man"
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Sam and Castiel follow up on a lead about the Mark of Cain. Dean and Rowena meet.

Dean Investigates - Supernatural Season 10 Episode 16
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"Paint It Black"
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Sam and Dean investigate a number of mysterious murders on Supernatural Season 10 Episode 16. Meanwhile, Rowena seeks out the Coven.

Sam Hunting - Supernatural Season 10 Episode 15
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"The Things They Carried"
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Sam and Dean's new case leads them to find Cole. But will they team up or is Cole still a threat to the Winchester brothers?

Cain Returns - Supernatural
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"The Executioner's Song"
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On Supernatural Season 10 Episode 14, Cain retuns while Rowena confronts Crowley when he bails on plans with his mother to help the Winchesters.

Dean Breaking Computers - Supernatural Season 10 Episode 13
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"Halt & Catch Fire"
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A ghost starts killing people through various electronic devices on Supernatural Season 10 Episode 13. Can Sam and Dean delete it?

Sam and Young Dean - Supernatural Season 10 Episode 12
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"About A Boy"
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Dean is transformed into his 14-year-old self after the Winchester brothers deal with an evil witch. Will Dean turn back into himself again?

Surprised Sam - Supernatural Season 10 Episode 11
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"There's No Place Like Home"
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An old friend returns to Supernatural. But Sam and Dean are still trying to deal with the Mark of Cain. We'll run this episode down when it airs!

I'll Cut You - Supernatural
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"The Hunter Games"
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After the massacre at the ranch, Dean, Sam and Castiel double their efforts to find a cure for the Mark of Cain but there is nothing in the lore that can help them.

Jimmy and his Girl - Supernatural
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"The Things We Left Behind"
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On Supernatural Season 10 Episode 9, Castiel finds Jimmy's daughter in a group home and calls on Sam and Dean to help him find her when she breaks out.

Handle with Care - Supernatural
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"Hibbing 911"
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On Supernatural, Jody Mills is required to attend a Sheriff's retreat and winds up partnered with an over-eager Sheriff who wants to bond.

Hannah and Castiel - Supernatural Season 10 Episode 7
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"Girls, Girls, Girls"
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Supernatural Seaso 10 Episode 7 is titled "Girls, Girls, Girls." It will find Sam and Dean investigating a brothel full of witches.

Getting a Clue - Supernatural Season 10 Episode 6
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"Ask Jeeves"
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On Supernatural Season 10 Epispde 6, Sam and Dean take a road trip. They aim to ensure Bobby's kin receive the fortune they are due after an heiress dies.

Lookin' Good - Supernatural Season 10 Episode 5
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"Fan Fiction"
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Supernatural celebrates its 200th episode with a bit of meta fiction when Sam and Dean discover a musical production about their lives at when they investigate the disappearance of a teacher.

Ridin' with a Werewolf - Supernatural
Watch Supernatural Season 10 Episode 4
"Paper Moon"
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On Supernatural, when werewolf attacks are reported Sam and Dean head out to see what is going on only to learn it is Kate, the werewolf they let live!

Can Crowley Help Castiel? - Supernatural
Watch Supernatural Season 10 Episode 3
"Soul Survivor"
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On Supernatural, when Crowley believes Dean's demonic antics are creating problems in hell, he turns to an unlikely source for help - Castiel.

Crowley Talks to Dean - Supernatural
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"Reichenbach"
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On Supernatural when Dean's aggression seems to grow out of control, he thinks it's just a side effect of being a Demon. Crowley has another reason for it.

Sing It, Demon Dean! - Supernatural
Watch Supernatural Season 10 Episode 1
"Black"
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This is the tenth season premiere for The CW Series Supernatural.

Supernatural Season 10 Quotes

Now I realize that there is no righteous path, it's just people trying to do their best in a world where it is far too easy to do your worst.

Castiel

Come on in darling, the water's warm.

Sam