Watch Grey's Anatomy Season 5 Episode 22 online via TV Fanatic with over 7 options to watch the Grey's Anatomy S5E22 full episode. Affiliates with free and paid streaming include Amazon, iTunes, Vudu, Netflix, YouTube Purchase, Google Play, and Verizon On Demand.
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As Grey's Anatomy turns 100, Meredith and Derek prepare to walk down the aisle as Izzie's condition brings back familiar (handsome!) symptoms.