Karen: Gosh, I haven't rooted this hard for a gay couple to get together on TV since Frasier and Niles.
Will: They were brothers.
Karen: I know.

Will: This is the most invasive, morally bankrupt thing…geez Louise, those guys are hot.
Karen: Yeah, well, they wouldn't be on TV if they weren't. It's not the BBC.

Jack: Now, I'm going to show you how to get over a guy the gay way.
Grace: Does it involve cardio?
Jack: Kind of. Mother always said the best way to get over one guy is to get under, behind, and sideways with another one.

It's a never ending buffet of men out there. What if I pick the stale cookie right as they bring out the cheesecake?

Jack

Trust me, Drew, no good has ever come of a man coming out to his wife. Don't you want to be vice president one day?

Jack

Remember to smile, but not like the clown from It.

You are so cute, and I love that you still have that new gay smell.

Jack

Isn't one month traditionally when the gay husband comes out to his wife? I believe the gift for that is a suitcase.

Will: Are you still seeing that married cop from Staten Island, or as Grace and I like to call him when you’re not around, your Staten Island Fairy?
Jack: I'm using that and not crediting you.

Vince: Did you see the two gay guys cake topper?
Will: Yeah.
Vince: We had to buy two straight couples and break them apart. So if you know any lesbians getting married, tell them we have a cake topper.

Will: It's two minutes of his time. What could possibly go wrong in two minutes?
Grace: Ask every girl who ever got pregnant at her prom.

I know something's wrong because you're over plucking your eyebrows. You look like an extra on Orange Is the New Black.

Grace [to Wil]

Will & Grace Quotes

Sorry I'm late but I got here as soon as I wanted to.

Karen

I'm sorry, I guess some people age like an anchorman and others like a meth head mother of nine.

Will