Dean: Yeah, well, I'll tell you one thing. At this point, I hope he's with Ruby.
Bobby: Why?
Dean: 'Cause killing her is the next big item on my to-do list.
Bobby: I thought you were on call for angel duty.
Dean: I am on call, in my car, on my way to murder the bitch.

If you walk out that door, don't you ever come back.

Dean

You don't know me. You never did, and you never will.

Sam

Dean: Well, it's about time. I've been screaming myself hoarse out here for about two and a half hours now.
Castiel: What do you want?
Dean: Well, you can start with what the hell happened in Illinois?
Castiel: What do you mean?

Dean: How long is this gonna go on?
Bobby: Here, let me look it up in my demon-detox manual. Oh, wait. No one ever wrote one.

Congrats, Sammy. You just bought yourself a benchwarmer seat to the Apocalypse.

Dean

Supernatural Season 4 Episode 21 Quotes

Dean: How long is this gonna go on?
Bobby: Here, let me look it up in my demon-detox manual. Oh, wait. No one ever wrote one.

Congrats, Sammy. You just bought yourself a benchwarmer seat to the Apocalypse.

Dean