Monse: Promise me nothing is going to change.
Everyone: Nothing is going to change.

Monse: If I leave you're going to forget about me.
Cesar: Me? Forget about you? Never. We're not going to forget about each other. We can never really leave each other. You know why? Because we made each other who we are. We are burned into each other's DNA, and it doesn't matter where you are, or what you do. When your heart beats, mine beats with it.
Monse: I can't leave you.
Cesar: You can't stay for me either. I swear to you I will be here when you come back, no matter how long it takes.

Monte: Don't waste this opportunity on some gangbanger. His life isn't going anywhere, but yours can.
Cesar: Your dad's right.
Monte: I'm sorry.
Cesar: Don't be. She needs to go.
Monte: Feel free to convince her. I need a break and a drink.

Just because you're from the streets doesn't mean you need to stay there. 

Monte

Oscar: Hermano, it's a new day. I don't need this shit. I want adult problems. Maybe have a wife, a kid. All I have right now is resentment and missed opportunities. I don't want that shit no more. It's time to give it away and start a new chapter.
Cesar: What if someone takes your power?
Oscar: Let 'em. You taught me the real power is all up here.

Oscar: These are your territories. As long as you stay in your territories, there's nothing to worry about. You have my word. We've had our head on a swivel too long. No más. We work together to clip problems before they become problems. You good?
19th Street gang member: Yeah. I want to make it to my 16th birthday.

Ruby: Life is fleeting. I have had more than one moment to know what that means. I don't have time to waste. I have to go with my gut. And my gut is telling me that I have to do what feels right. And what feels right is you.
Jasmine: So you got to do me?
Ruby: Hopefully, at some point.
Jasmine: I don't know. That's really forward of you, Ruby.
Ruby: I think you can handle it.
Jasmine: I-I don't know if I can. But I'm willing to try.

Ruby: Kissing you is not like kissing my abuelita. I was trying to--
Jasmine: Crush me?
Ruby: No!
Jasmine: Stab me in the heart?
Ruby: No!
Jasmine: Cut my soul in half and then pee on it?
Ruby: .No! I was just trying to protect you.

You'd be surprised by how much of the body can be sewn together.

Abuelita

Abuelita: Thank you.
Oscar: For what.
Abuelita: You know what.

Monse, I never got to tell him I was sorry. I never got to thank him for everything he has done for me. 

Cesar

Monse: Spooky's dead. He's processing losing the only real family that he has.
Ruby: No we're the only real family that he has.
Monse: Then act like it.

On My Block Quotes

Your name is Spooky, and you're afraid of ghosts?! 

Jamal

You know the worst part about growing up without a father? It's having to be a father to a brother without ever being a son.

Oscar