Derek: Meredith i am so sorry. Addison...what are you doing here?
Addison: You'd know if you'd bother to answer any one of my phone calls. (turns to Meredith) Hi. I'm Addison Shepherd
Meredith: Shepherd?
Addison: And you must be the woman who's been screwing my husband.

Men don't buy tampons!

George

The game. They say a person either has what it takes to play or they don't. My mother was one of the greats. Me on the other hand. I'm kinda screwed.

Meredith

[narrating] "The thing people forget is how good it can feel when you finally set secrets free. Whether good or bad, at least they're out in the open, like it or not. And once your secrets are out in the open, you don't have to hide behind them anymore. The problem with secrets is even when you think you're in control, you're not."

MEREDITH

DEREK: "Somewhere out there is a steak with your name on it, and maybe a bottle of wine."
MEREDITH: "This is why I keep you around."

[enraged, tackling Alex] "You gave me syphilis!?"

GEORGE

"You are lying. I know you’re lying. You know how I know? Cause you’re a bad liar!"

MIRANDA

CRISTINA: "Okay, I’m in."
MEREDITH: "I am so not involved in this."
CRISTINA: "Meredith, this is Fight Club, nobody talks about it."

PRESTON: "Bill is sterile?"
SURGEON: "And always has been."
GEORGE: "So who got his wife pregnant?"

DEREK: "Maybe we should, you know, make some rules."
MEREDITH: "We should."
DEREK: "Okay."
MEREDITH: "Okay."
DEREK: "Just for the record... I like the glow-in-the-dark ones."
MEREDITH: [laughs] "I bet you do."

MEREDITH: "So just for the record, you’d tell me if I need to get tested, right?"
DEREK: [whispers] "You think I have syphilis?"
MEREDITH: "No, I don't. It's just... I mean we never made any rules or anything... we never said we had rules and I wouldn’t hold it against you."
DEREK: "When would I have time to go out and get syphilis? You’re a handful enough as it is. And besides, we’re practically a condom ad."
MEREDITH: "Yeah...But no more glow-in-the-dark ones."

DEREK: "How goes our special super secret silent sunset surgery?" [pauses] "I've been practicing that."
MIRANDA: "You have too much time on your hands."

Grey's Anatomy Season 1 Quotes

[narrating] "At some point, you have to make a decision. Boundaries don't keep other people out, they fence you in. Life is messy, that's how we're made. So you can waste your life drawing lines or you can live your life crossing them. But there are some lines that are way too dangerous to cross. Here's what I know. If you're willing to throw caution to the wind and take a chance, the view from the other side... is spectacular."

MEREDITH

ALEX: "God, I smell good! You know what, it's the smell of an open heart surgery. It is awesome. It. Is. Awesome! You gotta smell me."
MEREDITH: "I don't want to smell you."
ALEX: [wraps arms around Mer] "Oh, yes you do!"
MEREDITH: [shoves Alex] "You've gotta to be kidding me! I've got more important things to deal with than you. I've got roommates, boy problems and family problems... You wanna act like a little frat boy bitch, that's fine. You wanna take credit for your saves and everybody elses, that's fine too. Just stay out of my face! And for the record you smell like crap!" [Derek walks in]
ALEX: [shrugs] "She attacked me." [Meredith attacks]
DEREK: [steps in] "Meredith, Meredith!" [to Alex] "You know, you might want to leave, before I change my mind and let her beat you to a pulp with her tiny, ineffectual fists."