[narrating] Bones break. Organs burst. Flesh tears. We can sew the flesh, repair the damage, ease the pain. But when life breaks down... when we break down... there's no science. No hard and fast rules. We just have to feel our way through. And to a surgeon there's nothing worse, and there's nothing better.

Meredith

[narrating] As surgeons we are trained to fix what's broken. The breaking point is our starting line... at work. But in our lives the breaking point is a sign of weakness and we'll do everything we can to avoid it.

Meredith

Yes. Horrible things DO happen. Happiness in the face of all of that? That's not the goal. Feeling the horrible and knowing that you're not gonna die from those feelings...that's the point.

Dr. Wyatt

Izzie: What are you doing in here?
Derek: I was thinking about making this my office when you move out.
Izzie: When I move out? When am I moving out?
Derek: Oh. Soon?

My patient's dying. I hate when I like them and they're dying.

Meredith

Lexie: Our guy's been in pain. Pain at a constant 8, for the last seven years, because of an inflamed nerve in his nose. It's crazy.
George: I wish I had an inflamed nerve in my nose.

Callie: Stop. You have to stop.
Mark: I can't.
Callie: Seriously. She hates it.
Mark: That's why I can't.

[to Callie] You want a spanking?

Mark

Erica: [to Callie] Look. We don't even know what we are yet. So, how does Mark Sloan know? Why are you talking to him instead of me?
Mark: Ladies... Am I interrupting something?
Erica: Your timing is perfect.
Mark: Really? You about to feel her up?

I can do this. I'm not married and cheating on my wife with my best friend. Everything is as it should be.

George

Eat the muffin, Mer. Taste the muffin. Remember. The muffin.

Izzie

Cristina: There's no way that guy has been living at an 8. He's a wimp. His 8? My 3. I can take pain.
Meredith: You can't talk to my boyfriend for 10 minutes.
Cristina: Well there's pain and then there's torture.

Grey's Anatomy Season 5 Episode 2 Quotes

Eat the muffin, Mer. Taste the muffin. Remember. The muffin.

Izzie

Cristina: There's no way that guy has been living at an 8. He's a wimp. His 8? My 3. I can take pain.
Meredith: You can't talk to my boyfriend for 10 minutes.
Cristina: Well there's pain and then there's torture.