PRESTON: "We have been through a lot this year."
DEREK: "And everybody else turned you down. Alright, what do I have to do?"
RICHARD: "Well, traditionally, the best man plans the bachelor party."
DEREK: "Drinks at Joe's after work."
PRESTON: "I knew you were the man for the job."

PRESTON: "Actually, Chief..."
DEREK: "You can't be his best man!"
RICHARD: "Why not?"
DEREK: "It's unethical; it's a conflict of interest. The man wants to be Chief of Surgery."
PRESTON: "Actually, Derek..."
DEREK: "Not that that's why you're asking..."
PRESTON: "I was going to ask you."
DEREK: "Ask me what? [pauses] Oh! Really?"

RICHARD: "Tomorrow's a big day."
PRESTON: "And apart from the fact that Cristina hasn't written her vows, my best man just cancelled, and it's still raining."
DEREK: "He's not ready."
RICHARD: "You're never ready. I certainly wasn't. And then, the minute I saw Adele coming down that aisle... Well. Have you picked your best man?"

RICHARD: "So, how you feeling, Preston? You ready?"
PRESTON: "Well, I'm always ready for surgery."
DEREK: "I think he's talking about the wedding."

MEREDITH: "It looks like a teeny tiny catfish."
RICHARD: "Close. See there? Those are spines. This is a candirú fish."
CRISTINA: "The penis fish? This guy has the penis fish! In his... in his... Wow!"

MARK: "Why? I mean, did she tell you why?"
DEREK: "What did you do to her, Mark?"
RICHARD: "She didn’t give a reason."
MARK: "Did she tell you where she was going?"
RICHARD: "All she said was she needed some time. To be happy and free, if I recall correctly. Excuse me."

MARK: "Has anybody seen Addison?"
RICHARD: "Uh, she’s gone."
MARK: "Gone?"
RICHARD: "She took a leave of absence."

RICHARD: "Go away!"
ADDISON: "But we can help!"
PRESTON: [to Addison] "No, WE can help."
ADDISON: "What's that supposed to mean?"
PRESTON: "He doesn't have any woman parts."
ADDISON: "Irrelevant."

MARK: "'I’m a friendly guy?'"
RICHARD: "Sloan…"
MARK: "She pressed 5 and got off at 3. She’d rather walk up two flights of stairs than flirt with you. Hell, she’d rather climb up the outside of the building."
RICHARD: "I wasn’t flirting."
MARK: "You’re telling me!"

RICHARD: "Sloan. You brought me to a bar. You know I don’t drink."
MARK: "Which is perfect. Better to keep your mind sharp. Let the ladies do the drinking."

RICHARD: "Addison, I wouldn’t know where to start."
ADDISON: "Ask me to dance."
RICHARD: "Well, there’s no dance floor."
ADDISON: "So? Ask me anyway."

RICHARD: "Well, you think about it. I mean, when you’re married you like to think you still have game."
ADDISON: "Practice on me."
RICHARD: "I’m sorry?"
ADDISON: "Mark’s right. I mean, he’s wrong about so many things, but he is right about this. You need to get back out there. So, practice."

Grey's Anatomy Quotes

Just because we can live without something, it doesn't mean we have to.

Meredith

Derek: I am calling post-it, Zola, Bailey, the tumors on the wall, ferryboat scrub caps. I thought D.C. was everything. I was wrong. You... you're everything. I love you and I'm not going to stop loving you. I can't live without you. I don't want to live without you, and I'm going to do everything in my power to prove it.
Meredith: I can live without you, but I don't want to. I don't ever want to.