Sheldon: I suppose there's no choice but to face the crying, angry accusations, and the high pitch wails of despair.
Penny: Yeah and who knows how Amy will react.

But, you two make such a cute couple. Like Bert and Ernie. You guys even teach me stuff about words and numbers.

Penny: Okay. Hang on. Are you saying some day that you and Amy might actually get physical?
Sheldon: It's a possibility.

You ever going to sleep with Amy?

Bernadette: Well, what if Hulk picked up Thor while Thor is holding the hammer.
Amy: Yeah?
Bernadette: Then by the transitive property of picking things up Hulk picked up the hammer.
Amy: No. Hulk picked up Thor. Thor picked up the hammer.
Penny: Okay, hang on. If I go to a bar and pick up a guy and he picks up a girl and then we all leave together. Did I pick up the girl?
Amy: Did that ever happen?
Penny: Hey, are we talking about me or are we talking about Thor?

Penny: If Harry Potter's wand can make decisions, why can't Thor's hammer?
Amy: Ok, if you're going to start comparing wands and hammers, I can't even take you seriously.

Penny: Oh, Thor. He's hot.
Stuart: Yeah, he kind of is.

Oh, this is the best. You have booze with breakfast on a Tuesday, you have a problem. You do it on the weekend, you have brunch.

Penny: Damn. You have more make-up than I do. You've got better make-up than I do. Yep, I'm borrowing ing this.
Leonard: Hey, hey, hey. This is my comic con make-up. I love you, but there are some things a man doesn't share with his girlfriend.

Penny: Molecules.
Leonard: Okay. come with me.
Penny: Where are we going?
Leonard: To my bedroom. So, I can take everything off but those glasses. And, maybe the boots.

Leonard: Can I tell you a secret?
Penny: What's that?
Leonard: All these women chasing me, I kinda do feel like Captain Kirk.
Penny: Can I tell you a secret?
Leonard: Sure.
Penny: Keep talking about Captain Kirk and we're all going to stop.
Leonard: Message ... received.

Penny: Is having a real-life girlfriend that has sex with you getting in the way of your board games.
Leonard: A little bit, yeah.

TBBT Quotes

Penny, there's only one cookie with something in the middle that solves life's problems, and that's an Oreo. Or a Nutter Butter, if you're in a pinch.

Sheldon

Leonard: Hi. I'm Leonard. You are beautiful. You pop, sparkle and buzz electric. I'm going to pick you up at eight, show you a night you will never forget.
Raj: Where are we going?