Izzie: This is absurd.
George: Hey...
Izzie: You shouldn't be sleeping in the On-Call room.

George: Did you only shave one leg?
Izzie: (starts crying) I know, I'm sorry!!!

You’re Dr. Bailey, you hear everything. And even if you haven’t heard everything I’m sure you heard.

I would've given my dad my heart if I could. If I could've saved him. I would've given him my heart.

George: No, see, I think it means you don't forgive me. And you don't know how to talk to me right now, and i mean look! You don't... you can't even look at me. You're so angry that i think the only way you can deal with me is to say you forgive me and what... we pretend it didn't happen? It happened, and you don't forgive me.
Callie: You're right, I don't.

George: Callie. You can't just forgive me. What I did to you, it's unforgivable.
Callie: That's how it works. That's what I forgive you means.

Izzie: No, shes saving all her rage and bloodshed for me. And she's gonna kill me in the cafeteria at lunch.
George: No she wouldn't.
Izzie: She breaks bones for a living George, she's crazy!
George: No shes not crazy.
Izzie: Well she is if she thinks I'm not gonna put up a fight.

George: Callie... you haven't said anything and... just say something... please, anything.
Callie: I forgive you.
George: What?
Callie: You made a mistake, but we took vows, 'til death do we part so...I forgive you.

George: Did you know how to do the procedure?
Richard: Are you saying that we're too old to learn the new ways, O'Malley?
George: No.
Richard: Are you saying we're old dogs who can't learn the tricks?
George: No. I just...
Mark: We're not old dogs.
Webber: We still got it.

Callie: Just say it.
George: I slept with Izzie.

George: Mrs. Burke
Mrs. Burke: I don't know you do I?
George: I'm George O'Malley, Burke's friend, Burke's guy.
Mrs. Burke: Hello, George O'Malley, Burke's friend, Burke's guy.

George: I Thought it was right but it wasn't.It's not!
Izzie: It's not.
George: I... I've got to tell her! I have to tell her that marriage is over. It's the right thing to do.
[he runs out, then comes back]
George: Did you see how I walked out of here all determined?
Izzie: You made me proud!

Grey's Anatomy Quotes

Everything comes apart at some point. We all will. It's the law. It's what we're designed to do. We have to face it, and accept it, and try to hold it together for as long as we can.

Meredith

Freezing, choking, getting tongue-tied--there's a reason it happens. We lose our words because the stakes are so high and we have so much to lose. We're petrified of saying too much, or saying it wrong. When the truth is,the only wrong thing you can say is nothing at all.

Jackson