Izzie: This is absurd.
George: Hey...
Izzie: You shouldn't be sleeping in the On-Call room.

George: Did you only shave one leg?
Izzie: (starts crying) I know, I'm sorry!!!

You’re Dr. Bailey, you hear everything. And even if you haven’t heard everything I’m sure you heard.

I would've given my dad my heart if I could. If I could've saved him. I would've given him my heart.

George: No, see, I think it means you don't forgive me. And you don't know how to talk to me right now, and i mean look! You don't... you can't even look at me. You're so angry that i think the only way you can deal with me is to say you forgive me and what... we pretend it didn't happen? It happened, and you don't forgive me.
Callie: You're right, I don't.

George: Callie. You can't just forgive me. What I did to you, it's unforgivable.
Callie: That's how it works. That's what I forgive you means.

Izzie: No, shes saving all her rage and bloodshed for me. And she's gonna kill me in the cafeteria at lunch.
George: No she wouldn't.
Izzie: She breaks bones for a living George, she's crazy!
George: No shes not crazy.
Izzie: Well she is if she thinks I'm not gonna put up a fight.

George: Callie... you haven't said anything and... just say something... please, anything.
Callie: I forgive you.
George: What?
Callie: You made a mistake, but we took vows, 'til death do we part so...I forgive you.

George: Did you know how to do the procedure?
Richard: Are you saying that we're too old to learn the new ways, O'Malley?
George: No.
Richard: Are you saying we're old dogs who can't learn the tricks?
George: No. I just...
Mark: We're not old dogs.
Webber: We still got it.

Callie: Just say it.
George: I slept with Izzie.

George: Mrs. Burke
Mrs. Burke: I don't know you do I?
George: I'm George O'Malley, Burke's friend, Burke's guy.
Mrs. Burke: Hello, George O'Malley, Burke's friend, Burke's guy.

George: I Thought it was right but it wasn't.It's not!
Izzie: It's not.
George: I... I've got to tell her! I have to tell her that marriage is over. It's the right thing to do.
[he runs out, then comes back]
George: Did you see how I walked out of here all determined?
Izzie: You made me proud!

Grey's Anatomy Quotes

Amelia: I think I'm falling in love with Owen Hunt, and I'm really afraid that it's gonna destroy me.
Derek: It wouldn't be love if it didn't.

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith