Izzie: This is absurd.
George: Hey...
Izzie: You shouldn't be sleeping in the On-Call room.

George: Did you only shave one leg?
Izzie: (starts crying) I know, I'm sorry!!!

You’re Dr. Bailey, you hear everything. And even if you haven’t heard everything I’m sure you heard.

I would've given my dad my heart if I could. If I could've saved him. I would've given him my heart.

George: No, see, I think it means you don't forgive me. And you don't know how to talk to me right now, and i mean look! You don't... you can't even look at me. You're so angry that i think the only way you can deal with me is to say you forgive me and what... we pretend it didn't happen? It happened, and you don't forgive me.
Callie: You're right, I don't.

George: Callie. You can't just forgive me. What I did to you, it's unforgivable.
Callie: That's how it works. That's what I forgive you means.

Izzie: No, shes saving all her rage and bloodshed for me. And she's gonna kill me in the cafeteria at lunch.
George: No she wouldn't.
Izzie: She breaks bones for a living George, she's crazy!
George: No shes not crazy.
Izzie: Well she is if she thinks I'm not gonna put up a fight.

George: Callie... you haven't said anything and... just say something... please, anything.
Callie: I forgive you.
George: What?
Callie: You made a mistake, but we took vows, 'til death do we part so...I forgive you.

George: Did you know how to do the procedure?
Richard: Are you saying that we're too old to learn the new ways, O'Malley?
George: No.
Richard: Are you saying we're old dogs who can't learn the tricks?
George: No. I just...
Mark: We're not old dogs.
Webber: We still got it.

Callie: Just say it.
George: I slept with Izzie.

George: Mrs. Burke
Mrs. Burke: I don't know you do I?
George: I'm George O'Malley, Burke's friend, Burke's guy.
Mrs. Burke: Hello, George O'Malley, Burke's friend, Burke's guy.

George: I Thought it was right but it wasn't.It's not!
Izzie: It's not.
George: I... I've got to tell her! I have to tell her that marriage is over. It's the right thing to do.
[he runs out, then comes back]
George: Did you see how I walked out of here all determined?
Izzie: You made me proud!

Grey's Anatomy Quotes

[narrating] "At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing where we all keep our distance and pretend not to care about each other, it's usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them. The people that are still with you at the end of the day, those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need."

MEREDITH

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)