T.R. Knight, who plays Dr. George O'Malley.
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The Grey's Anatomy star talked with the famous talk show host in January 2007.
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T.R. Knight, Isaiah Washington, Kate Walsh and Katherine Heigl have some fun after the Emmy Awards.
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T.R. Knight, from his recent Sesame Street appearance.
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T.R. Knight has his "I" on the case as a private detective on Sesame Street.
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The letter I, that is.
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The cast of Grey's Anatomy, circa Season Two.
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The cast of Grey's Anatomy, decked out in black.
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Grey's Anatomy Quotes

The first time I kissed my wife, she wasn't my wife then, she was just this girl in a bar. But when we kissed, it was like, I gotta tell you, it was like I'd never kissed any other woman before. It was like my first kiss. The right kiss.

Derek

[narrating] "At some point, you have to make a decision. Boundaries don't keep other people out, they fence you in. Life is messy, that's how we're made. So you can waste your life drawing lines or you can live your life crossing them. But there are some lines that are way too dangerous to cross. Here's what I know. If you're willing to throw caution to the wind and take a chance, the view from the other side... is spectacular."

MEREDITH