Raj meets a new lady at the comic book store, and she makes him question his relationship with Emily. Well, that may actually be a good thing, since Emily seems a bit crazy anyway. Is anyone else finding it difficult to trust that chick?
Sheldon is excited when Meemaw comes to visit, but Meemaw is less than impressed with Amy Farrah Fowler. It's likely no one is actually good enough for her "Moon Pie," and she isn't afraid to make that fact known.
The gang decides to go Sheldon free for a weekend after having to deal with him while he's ill for a week on The Big Bang Theory. "The Empathy Optimization" is the 13th episode of the show's ninth season.