This is a scene from the 5/17/10 episode of The Big Bang Theory. Yes, that's Mayim Bialik guest-starring in the sitcom.
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Judy Greer guest starred on The Big Bang Theory as Dr. Plimpton, a famous physicist that Sheldon invites to spend the weekend at the place.
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Penny returns Sheldon to Leonard after their trip to Disney Land. The couple is sharing custody over the nerd.
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Sara Gilbert is seen here on The Big Bang Theory. She plays the character of Leslie.
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This is a photo from the episode "The Wheaton Recurrence." There's really not much to say about it, is there?
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A picture after Wil Wheaton just bowled as Sheldon prepares to counter.
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Penny and Leonard go bowling and Leoanrd sure does seem to be celebrating something.
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Wil Wheaton calls out Sheldon as the two of them meet in the bowling alley.
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Sheldon has a shirt made that says "The Wesley Crushers" for his bowl off with Wil Wheaton. Get it? No? Wheaton played Wesley on Star Trek.
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Sheldon goes up against Wil Wheaton in the ultimate bowl off between rivals.
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Poor Penny attempts to go bowling as Raj and Wolowitz watch on and drool.
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Sheldon goes up against his nemesis, a characterized version of Wil Wheaton, in bowling on The Big Bang Theory.
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TBBT Quotes

Penny: What actor holds the record for being named People magazine's Sexiest Man Alive?
Sheldon: William Shatner!
Leonard: I don't think it's Shatner.
Sheldon: Then it's got to be Patrick Stewart

Penny: Hey, Sheldon, did you change your Wi-Fi password again?
Sheldon: Yes, it's "Penny, get your own Wi-Fi." No spaces.