Sam may not be able to see the ghost, but he's ready for anything. It looks like a tough battle this go around, but we all know the Winchester brothers will be able to handle this. C'mon! It's Sam and Dean!
Sam and Dean are pretty focused on whatever Sheriff Donna is talking about. While she may be gushing over getting to see the Winchester brothers again, or she's telling them about the latest supernatural situation.
What better way to start a case then to get a tour of the police station from Sheriff Donna? It's great to see the three reunited, and they definitely have a lot to catch up on since their last hangout.