DeLuca may be wondering what has brought his sister all the way from Italy to GSM because it can't possibly be just to visit her charming brother. Siblings always have ulterior motives. Will he be the person behind his sister making a startling new discovery?
Is Maggie part of the team of doctors helping Megan? It's always good to have a child prodigy on the case. What if she's working with DeLuca's sister instead? That could certainly make things interesting given her history with DeLuca.
How does DeLuca spend a day off? Coming into the hospital anyway. Maybe he wanted to check in on his sister who has mysteriously appeared at GSM with a controversial research trial that will get everyone talking.
Meredith and the others are busy coming up with a new plan to help Megan Hunt, but Amelia busies herself with a complicated new case. Could she be giving everyone the space they need, or is she avoiding Owen because a sibling rising from the dead stirs up feelings?
Things did not end well between Arizona and Eliza in the season finale. Their relationship came to an end just as Eliza's job at GSM came to an end. Either a significant amount of time has passed, or Arizona isn't that torn up about it. Could it have anything to do with her roommate's relative popping up?
Teddy is a familiar face to many, but there are new faces appearing in the premiere too. Who are all these new faces? Will there be any more old faces reappearing for nostalgia's sake? Tune in to find out!
Megan is with the best doctors in the country, so we're told, but that isn't enough to assuage Nathan's worry. He is impatiently waiting for more information on Megan's condition and a plan for what the others will do about it.
Nathan awaits an update while someone operates on his former fiancee. Or is she his current fiancee? Ex-lover? New lover? It's all so deliciously messy. Nathan won't be able to figure out the state of his relationship with Megan until she's in the clear.
Teddy is back and helping the team tend to Megan Hunt, but things are bound to get awkward. Teddy hasn't exactly been speaking to her former best friend Owen, since she left after Henry's death. Since she's left, he and Cristina are divorced, her former mentee is long gone, and Owen has remarried to Amelia, Derek's (who has since died) little sister. Will old feelings resurface? You miss a lot when you stay away from GSM for too long!
Jackson is back, but is Japril? Who knows! Things were left uncertain in the finale when he never reunited with April after their trip in Montana, but he continued to get closer to Maggie. April saw something between them that even they haven't acknowledged yet. Is Jackson off the market now that Maggie is in his life, or are they just platonic?
It took Nathan a long time to get past Megan's "death," and now he has to relive it all over again when she's alive but not in the best condition. It has to be like reliving the heartache all over again, with the extra paranoia of not knowing if he could lose her all over again. Poor Nathan!
There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.
MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore." DEREK: "This thing with us is finished. It's over." MEREDITH: "Finally." DEREK: "Yeah, it's done." MEREDITH: "It is done."