In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," Dr. Hahn looks on. What will the season bring for Erica (Brooke Smith)?
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Derek Shepherd looks on with those amazing eyes in the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me." But will McDreamy by okay in this episode?
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," and in every episode of Grey's Anatomy, Izzie is unmistakable. She's the best ... but also always close to trouble.
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Meredith helps out with patients as the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," is in full, emotional swing.
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Dr. Cristina Yang in a still photo from the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me." Will this episode bring her a new love interest?
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," Derek Shepherd looks as handsome as ever. But will he be involved in the major car wreck shown at the beginning?
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," guest stars Bernadette Peters and Kathy Baker share the same expressions of concern. Will they be alright?
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She's our girl. In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," a lot of people will be wondering if this is the last season for Izzie Stevens (Katherine Heigl).
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," Dr. Stevens is seen with some of Seattle Grace's newest patients.
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," Bernadette Peters is one of the primary guest stars. Looking forward to seeing what she brings to Seattle Grace!
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," a couple of new and interesting patients are admitted to Seattle Grace.
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," Kathy Baker guest stars as one of the patients admitted to Seattle Grace after this episode's major trauma.
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Grey's Anatomy Season 5 Episode 1 Quotes

[narrating] We all remember the bed time stories of our childhood. The shoe fit Cinderella, the frog was turned into a prince, sleeping beauty was awakened with a kiss. Once upon a time and then they lived happily ever after. Fairy tales. The stuff of dreams. the problem is, fairy tales don't come true. It's the other stories. The ones that start in dark and stormy nights and end in the unspeakable. The nightmares always seem to become the reality.

Meredith

Meredith: What happened!?
Cristina: A bus in front of him hit a telephone pole. He tried to swerve and miss it, but ...
Meredith: How bad is it?
Richard: Meredith -
Cristina: Meredith, you're gonna have to be strong.

Grey's Anatomy Season 5 Episode 1 Music

  Song Artist
Song Youthless Beck
Song Wins Jade McNelis
Song Jungle Drum Grey's Anatomy Emiliana Torrini