Lexie Smiles

Lexie Smiles

Lexie Grey flashes a smile at Seattle Grace. Will the interns grow to love or hate this new cutie?
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Meredith Looks Distraught

Meredith Looks Distraught

Dr. Meredith Grey has a pouty, upset look on her face in this photo. We're accustomed to seeing this expression by now!
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So McHandsome

So McHandsome

Derek Shepherd is still one who can make heads snap with his good looks. And fix heads with his mad skillz as a brain surgeon! What a combination.
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Still Sexy After All These Years

Still Sexy After All These Years

The wear and tear of life at Seattle Grace has done little to diminish the sexiness of Derek "McDreamy" Shepherd. Nor do we expect it to.
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I'm the Girl From the Bar!

I'm the Girl From the Bar!

Meredith is none too thrilled about the new girl Derek met at the bar. The fact that it's her sister can't help matters, either.
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Interns on the Run

Interns on the Run

Because Bailey is on the warpath? Because Mer and Der are hooking up in the on-call room and they want to watch? Who knows!
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Izzie's Bitches!

Izzie's Bitches!

Izzie has a new group of interns following her around. We will have to see how Dr. Stevens adjusts to being the one bossing peeps around instead of in the doghouse.
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Bailey Bosses Karev

Bailey Bosses Karev

Miranda tells Alex Karev who's boss around here. As if there were any doubt about that since his first days as an intern!
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Good Friends on GA

Good Friends on GA

Izzie and Alex used to be an item, but now they're just good friends. It's nice to see for fans of both characters.
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Bitter Bailey?

Bitter Bailey?

Rumor has it that Miranda Bailey is a little bit bitter and back to her bad-ass self in Season Four. Izzie Stevens could attest to this.
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Grey's Anatomy Season 4 Episode 1 Quotes

I tell you that I love you, and not one word? For 17 days? Where have you been?

Izzie

[narrating] In the practice of medicine, change is inevitable. New surgical techniques are created, procedures are updated, levels of expertise increase. Innovation is everything, nothing remains the same for long. We either adapt to change, or ... we get left behind.

Meredith