Izzie restrains a young visitor to the hospital. She's having quite the hectic day at the office.
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Eh, that couple nickname just doesn't work. Neither does the chemistry between these characters. Right, fans?
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What does the future hold for Meredith Grey and Derek Shepherd? Hopefully, only love. But we know it's never easy.
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Lexie Grey. Meredith Grey. Face-off. What will transpire as the two sisters must work together at Seattle Grace?
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Lexie Grey flashes a smile at Seattle Grace. Will the interns grow to love or hate this new cutie?
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Dr. Meredith Grey has a pouty, upset look on her face in this photo. We're accustomed to seeing this expression by now!
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Derek Shepherd is still one who can make heads snap with his good looks. And fix heads with his mad skillz as a brain surgeon! What a combination.
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The wear and tear of life at Seattle Grace has done little to diminish the sexiness of Derek "McDreamy" Shepherd. Nor do we expect it to.
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Grey's Anatomy Season 4 Episode 1 Quotes

I tell you that I love you, and not one word? For 17 days? Where have you been?

Izzie

[narrating] In the practice of medicine, change is inevitable. New surgical techniques are created, procedures are updated, levels of expertise increase. Innovation is everything, nothing remains the same for long. We either adapt to change, or ... we get left behind.

Meredith