Run Ike, Run!
The boys help Ike escape when they think a circumcision means the end of Ike's penis.

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South Park
South Park Season 2 Episode 4: "Ike's Wee Wee"
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South Park Season 2 Episode 4 Quotes

Stan: (about Kyle telling his parents) Dude, you shouldn't have told them that; now they're gonna go find him and cut off his penis!
Cartman: Fireman.
Kyle: Ah, who the hell cares? He's not even my responsibility!
(Kenny falls in an empty grave; the gravestone breaks in half and falls on him, killing him as well.)
Stan: Oh, my god! They killed Kenny!
Kyle: You bastards.

Stan: Why do dogs have cold noses?
Mr. Mackey: Uuuhh.. well I'm not sure.