Derek, Lexie, Cristina
Derek Shepherd (Patrick Dempsey), Lexie Grey (Chyler Leigh) and Cristina Yang (Sandra Oh) in the episode called "Physical Attraction, Chemical Reaction," from Season Four of Grey's Anatomy.

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Grey's Anatomy Season 4 Episode 7 Quotes

Meredith: [narrating] Before we were doctors, we were med students, which meant we spend a lot of time of studying chemistry. Organic chemistry, biochemistry, we learned it all. But when you're talking about human chemistry only one thing matters: either you've got it or you don't.

Derek: What's new with you?
Meredith: I saw my half-sister half naked.