Mark and Derek Smile

Mark and Derek Smile

Attendings Mark and Derek smile in a promotional photo from "Life During Wartime," shot for the fifth season of Grey's Anatomy.
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Life During Wartime

Life During Wartime

It's a new day at Seattle Grace and a new doctor - Owen Hunt - is already shaking things up.
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Mark and Derek Look On

Mark and Derek Look On

In this picture from "Here Comes the Flood," from the fifth season of Grey's Anatomy, Mark and Derek listen as Richard addresses the staff.
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Mark Sloan, Erica Hahn

Mark Sloan, Erica Hahn

In a photo from "Here Comes the Flood," Mark Sloan and Erica Hahn share a conversation while the Chief talks. What could it be about?
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Callie Torres, Mark Sloan

Callie Torres, Mark Sloan

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Callie and Mark have a conversation outside Seattle Grace. Will they get together?
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Mark Sloan and Callie Torres

Mark Sloan and Callie Torres

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Callie and Mark have a conversation outside Seattle Grace. What's to come of their relationship, if anything?
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Torres and Sloan

Torres and Sloan

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Callie and Mark have a conversation outside Seattle Grace. What's to come of them?
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Mark and Callie

Mark and Callie

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Callie and Mark share a moment outside the hospital. What's to come of these two?
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Richard, Derek and Mark

Richard, Derek and Mark

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Derek, Mark and Richard are seen in a rare scene outside Seattle Grace. Where is it?
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Mark Sloan and Izzie Steves

Mark Sloan and Izzie Steves

In a still shot from "Losing My Mind," from the fourth season of Grey's Anatomy, Izzie and Mark have a serious conversation in the halls of Seattle Grace.
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Isobel and Mark

Isobel and Mark

In a still shot from "Losing My Mind," from the fourth season of Grey's Anatomy, Mark and Izzie have a serious conversation at Seattle Grace.
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Bizarre Love Triangle?

Bizarre Love Triangle?

Maybe, and not quite the way you think! Callie Torres, Erica Hahn and Mark Sloan have a conversation in "The Becoming."
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Grey's Anatomy Quotes

Freezing, choking, getting tongue-tied--there's a reason it happens. We lose our words because the stakes are so high and we have so much to lose. We're petrified of saying too much, or saying it wrong. When the truth is,the only wrong thing you can say is nothing at all.

Jackson

Everything comes apart at some point. We all will. It's the law. It's what we're designed to do. We have to face it, and accept it, and try to hold it together for as long as we can.

Meredith