Attendings Mark and Derek smile in a promotional photo from "Life During Wartime," shot for the fifth season of Grey's Anatomy.
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It's a new day at Seattle Grace and a new doctor - Owen Hunt - is already shaking things up.
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In this picture from "Here Comes the Flood," from the fifth season of Grey's Anatomy, Mark and Derek listen as Richard addresses the staff.
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In a photo from "Here Comes the Flood," Mark Sloan and Erica Hahn share a conversation while the Chief talks. What could it be about?
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In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Callie and Mark have a conversation outside Seattle Grace. Will they get together?
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In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Callie and Mark have a conversation outside Seattle Grace. What's to come of their relationship, if anything?
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In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Callie and Mark have a conversation outside Seattle Grace. What's to come of them?
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In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Callie and Mark share a moment outside the hospital. What's to come of these two?
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In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Derek, Mark and Richard are seen in a rare scene outside Seattle Grace. Where is it?
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In a still shot from "Losing My Mind," from the fourth season of Grey's Anatomy, Izzie and Mark have a serious conversation in the halls of Seattle Grace.
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In a still shot from "Losing My Mind," from the fourth season of Grey's Anatomy, Mark and Izzie have a serious conversation at Seattle Grace.
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Maybe, and not quite the way you think! Callie Torres, Erica Hahn and Mark Sloan have a conversation in "The Becoming."
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Grey's Anatomy Quotes

Meredith: You're me.
Amelia: What?
Meredith: You're me before Derek. I can be here for you. I can do this. I get you. I can be a twisted sister for you. Just tell me how do you want to play this?

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)