As Alex Karev waits, Izzie Stevens walks down the aisle to him, beaming and looking positively radiant despite her ailing condition.
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Izzie stumbled on her way down the aisle, but George stepped in and helped his old friend make it to the steps, where she exchanged vows with Alex. Tear.
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It was a sweet scene when George gave away Izzie to Alex at the wedding, when she became weak and could not walk under her own power. Tears were shed at this website.
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Alex and Izzie get married in "What a Difference a Day Makes," from the fifth season of Grey's Anatomy. What an emotional, 100th episode this was.
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Izzie fake-codes to get Meredith out of the bathroom, but she's really feeling the impact of chemo pretty hard.
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Izzie Stevens is reunited with her mother, but will that be a good thing, or is this another relationship destined to cause more harm than good?
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Izzie's mom makes an appearance in "No Good at Saying Sorry," the April 30 episode of Grey's Anatomy, and Izzie is not looking altogether thrilled in this picture at least.
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Izzie's mom makes her first appearance on Grey's Anatomy. Somehow we imagine this is not going to go swimmingly for our girl.
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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith