Seattle Grace often falls into that category! George attempts to sort through some of the chaos in "Kung Fu Fighting."
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... Mouse? George meets a woman dressed in costume. Hey, it's Halloween and anything goes.
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George and Izzie. Their status continues to confound and cause great debate among Grey's Anatomy fans. Where will this love triangle (with these two and Callie Torres) lead?
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You don't see George too happy these days, so this photo of him smiling at Izzie comes as a rare sight. Will it last?
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Richard talks with George and Lexie about a patient. The Chief is always a steady, strong presence at the hospital.
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Izzie and George may very well be in love... but it does not look like they will last. Or does it? The writers have kept us guessing to this point.
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George and Lexie chat as she wears an interesting outfit. We like watching these two interact. She is growing on us!
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Failing his internship exam, cheating on his wife, possibly falling for his best friend... George O'Malley has been through a lot. Where will his character go next?
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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old, in your arms. I don't want 48 uninterrupted hours. I want a lifetime. Mmm. Do you see what happens? I say things like that and you fight the urge to run in the opposite direction. It's okay, I understand. I didn't, but now I do, I do. You're just getting started and I've been doing this for a long time now. Deep down, you're still an intern, and you're not ready.

Derek