Derek with Callie in the sixth episode of Grey's Anatomy Season 10, "Second Opinion."
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Callie with Derek in the sixth episode of Grey's Anatomy Season 10, "Second Opinion."
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Patrick Dempsey as Derek Shepherd on Grey's Anatomy, in his new role as an instructor. How do you think he will transition to this new role?
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Patrick Dempsey as Derek Shepherd on Grey's Anatomy, in his new role as an instructor. How do you think he'll handle it?
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Patrick Dempsey as Derek Shepherd on Grey's Anatomy, in his new role as an instructor.
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Patrick Dempsey as Dr. Derek Shepherd on Grey's Anatomy in a new Season 9 promo pic.
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A scene from the Season 8 finale of Grey's Anatomy.
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Meredith and Derek in a photo from the Grey's Anatomy Season 9 premiere. So sweet.
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Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.