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J.D. tries to break up with Neena, as she represents Mr. Corman in his lawsuit against Turk; Elliot pretends to be a male doctor to avoid issues with a sexist patient who's a member of the board.
Lucas takes Anna to the formal night but at the end of the night, someone else is in his arms. And when Brooke finally learns the truth ...
When Alan meets Nancy (Kelley West) at the grocery store, she fulfills all his fantasies, forcing Charlie to take care of Jake while he's distracted. After knowing Nancy for just a few days, Alan decides to ask her to marry him making Charlie to try and stop him, even getting Evelyn to help.
Gob commits to building a model home in two weeks and the whole family helps; Lindsay buys a cream made from diamonds.
J.D. and Cox have to deal with a manipulative malpractice lawyer, Neena Broderick (Julianna Margulies); Turk tries to avoid a hypochondriac patient Harvery (Richard Kind); Elliot steers Doug on a new path.
The girls of Tree Hill have a slumber party, at which time secrets are revealed and bonds are made. Meanwhile, Nathan and Lucas embark o...
Charlie and Alan hire Berta's sister to cater a party their mom forces them to have for her.
Lynette butts heads with Maisy Gibbons (Sharon Lawrence) at the twins' school over a play. Susan investigates the mystery of Zach's sudden disappearance.
Michael and George Michael leave for Phoenix, but end up returning; Lindsay wants an open marriage sending Tobias to join the Blue Man Group.
The opening of Karen's all-ages club "Tric" brings drama and discord to the Tree Hill crowd. After Chris quits his gig on the night of t...