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After getting rejected at the bar, Charlie learns about a website that exposes his lifestyle. Charlie sets to find out who created the site, making amends with all girls he hurt.
Gabrielle organizes a Halston fashion show for charity highlighting the ladies of Wisteria Lane. John's mother, Helen Rowlan (Kathryn Harrold) thinks her son is sleeping with Susan and not Gabrielle, but Gabrielle soon confesses.
George Sr. gets jealous over a budding relationship between Lucille and Oscar; The prosecutor shows up with new evidence in the case.
J.D. addresses a group of pre-med students about being a doctor and he and the staff reminisce about their best moments; Elliot faces her fear of children when left in charge of a ten year old.
After Ice reveals that George Sr. died in Mexico, the family holds a wake.
Nathan is concerned about Lucas' health, so he tells Karen that Lucas didn't take the heart test. Dan offers Keith the chance to continu...
When Charlie has to write a theme song for a comic book, Oshikuru, Jake is a fan of, he tries to enlist his help. Meanwhile, Alan finds out more about Rose as he hangs out with her.
The aftermath of Bree's son Andrew running over Carlos' mother. Susan grows suspicious of Mike's intentions of moving to Wisteria Lane. Lynette reaches the breaking point in her addiction to ADD medication.
J.D. befriends the son (Matthew Perry) of a noted singer who refuses to donate a kidney to his dying father; Carla and Jordan teach Elliot to use her sexuality to her advantage.
When Charlie leaves the house to avoid a date he can't stand, he ends up at the coffee shop where he runs into his old girlfriend, Lisa (Denise Richards), who is now a divorcee with a baby. Jake tries to justify to his father why he isn't doing well in school.