Michael Bluth is the second oldest Bluth son, but the most competent one.  When George Sr. went to jail, it was Michael who was stuck running Bluth Company and keeping the family together.  Michael's wife, Tracey, died of ovarian cancer two years prior to the first episode and left him to raise George Michael on his own.

Michael Bluth Quotes

Maeby: Do you guys know where I can get one of those gold necklaces with a "T" on it?
Michael: That's a cross.
Maeby: Across from where?

Well, I'm sorry. It's just it's too late. I'm truly sorry, but I'm moving to Phoenix. I got a job. (long pause) It's something you apply for, and then they pay you to, um ... never mind. I don't want to ruin the surprise.

Michael
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Arrested Development Quotes

Okay, we are just about ass-to-ankles back here, Maeby. Do you want to hop on your cousin's lap there, please?

Tobias

(Regarding Buster) Maybe it was the eleven months he spent in the womb. The doctor said there were claw marks on the walls of her uterus. But he was her 'miracle baby'. And I-I was just too burnt out on raising you guys to care. So... He turned out a little soft, you know...

George Sr.