Lisa Marie Simpson, voiced by Yeardley Smith, is Homer and Marge's oldest duaghter and the middle child on The Simpsons.  Lisa is very intelligent, plays the saxophone, is a vegetarian, Buddhist, and definitely a bit of a young political activist.  She's basically the complete opposite of her brother, Bart.

Lisa Simpson Quotes

(Homer hits a steel deer statue with his car)
Homer: D'oh!
Lisa: A deer!
Marge: A female deer!

Homer: What's the quickest, cheapest, easiest way to do something with you?
Lisa: Uh, take us to the video store?
Homer: Anything for my little girl.

The Simpsons Quotes

Homer: (Wearing glasses) The sum of the square roots of any two sides of an isosceles triangle is equal to the square root of the remaining side!
Man: (From inside a bathroom stall.) That's a right triangle, you idiot!
Homer: D'oh!

You know, you remind me of a poem I can't remember, and a song that may never have existed, and a place I'm not sure I've ever been to.

Grampa