A surgical resident from Mercy West Hospital, Jackson Avery is also called "pretty boy," especially by Cristina Yang.
He is a grandson of the famous surgeon, Dr. Harper Avery. He develops a crush on Cristina, and while inebriated he kisses her at a party, but Cristina breaks the kiss.
In the 6th season finale, he is told by Dr. Shepherd that there is a lockdown in the hospital and is later left by Dr. Hunt and Dr. Altman in the OR with 2 nurses and 1 anesthesiologist.
He is the one who decides that Yang should operate on Shepherd in order to save him. When Mr. Clark (the shooter) takes the OR hostage, he disconnects Shepherd in order to make everyone believe that he is dead until Mr. Clark leaves the room.
It is also revealed later in season 7 that Avery suffers from traumatic nightmares.