What happened to Karen?
That's what everyone joined forces to find out on Will & Grace Season 10 Episode 2 when it emerged that she was MIA since her husband found out about her affair.
With little leads, Will, Grace, and Jack decided they would leave no stone unturned to make sure their friend was okay.
However, a shocking twist in the tale made them worry that something terrible could have happened.
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Paul Dailly is the Associate Editor for TV Fanatic. Follow him on Twitter.