"Very Big" Meredith-Derek Story Coming Up on Grey's Anatomy This Spring

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Want more Meredith and Derek, Grey's Anatomy fans? You're in luck.

The Alzheimer's clinical trial, which the golden couple has been laboring over this season, will soon become the catalyst for a new storyline, according to TV Guide.

"We've been using the clinical trial for a while and it's going to launch into a very big story about them as we head towards the end of the season," Shonda Rhimes says.

Any theories on what that might entail? A legal wedding, perhaps?

Mer and Der Look On

Meredith and Derek have been on the back burner at times this season.

Cristina and her PTSD. Lexie and Mark's relationship. Callie's pregnancy and tribulations with Arizona. All of this has been great, but left some yearning for more MerDer.

This season has been especially unfortunate for Mer, who tragically suffered a miscarriage in the Season 6 finale, then took fertility drugs that left her temporarily blind.

"Meredith and Derek have been dealing with infertility, and it's starting to be a really sore point," Rhimes said, hinting that the pregnancies around her haven't helped.

"Part of [the musical episode] is about really bringing up how painful it is for Meredith watching other people get pregnant, have babies and deal with that other stuff."

Think it'll happen for them this spring? Sound off below.

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Grey's Anatomy Quotes

Arizona: Oh my God! I mean, I understand why you're into her. She's hot. Wait, she likes you?
Nathan: What? I mean, I'm going to try not to be offended at that.
Arizona: No, no, no. It's just that Derek was, Derek was epic for her. They were the great love story. I mean, that girl's heart beat for Derek Shepherd. It just, it never occurred to me that she would ever be with anyone else. He was perfect. He was everything. That man turned her world. It, I spooked you. Don't be spooked.

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."