We hope you've got a box of tissues handy, or perhaps two, because you can expect to use them when Grey's Anatomy returns for its sixth season on Thursday, September 24.
Jessica Capshaw, the newest series regular (Dr. Arizona Robbins), teases the aftermath of George's departure and how things will be different on the set without T.R. Knight.
"Heavy" is the best way to describe this season, as compared to Season 5.
Also, with Amy Brenneman's comment on the drama at Grey's Anatomy, Jessica reveals how she deals with 17-hour workdays (ahem, Katherine Heigl), since she also has a child.
Most importantly, the 33-year-old actress spills on just how Callie Torres' (Sara Ramirez) and Arizona Robbins' budding relationship is going to progress in this coming season.
Check out the E! News video below to get the details on why the Season Six premiere will be the best yet, and then hit the comments below to share your impressions ...
[video url="http://www.tvfanatic.com/videos/jessica-capshaw-interview/" title="Jessica Capshaw Interview"][/video]