Grey's Anatomy Spoilers: George's Departure

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With all the attention paid to whether or not Izzie will pass away tomorrow night, another major question has been more or less overlooked: Does this week's fifth season finale mark the final episode for another beloved character, Dr. George O'Malley?

Here's what TV Guide has to say in its spoiler chat ...

Q: What can you spill about the two-hour Grey's Anatomy season finale? Are we definitely saying goodbye to George and T.R. Knight?

A: Yes, there are rumors swirling that the finale not only paves the way for George's departure from Seattle Grace, but perhaps also his exit from this plane of existence as well.

I presented said scuttlebutt to Chyler Leigh (who plays Lexie), and asked if she feels she's shared the Grey's Anatomy set with Knight a final time. "Not that I know of," she said. "I'm not even sure T.R. knows [what the future holds]. I don't think anybody knows what's going to happen."

Well, nobody except Shonda Rhimes, that is.

A Final Farewell?

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

Arizona: Oh my God! I mean, I understand why you're into her. She's hot. Wait, she likes you?
Nathan: What? I mean, I'm going to try not to be offended at that.
Arizona: No, no, no. It's just that Derek was, Derek was epic for her. They were the great love story. I mean, that girl's heart beat for Derek Shepherd. It just, it never occurred to me that she would ever be with anyone else. He was perfect. He was everything. That man turned her world. It, I spooked you. Don't be spooked.