Grey's Anatomy Stars Leaving Show, Other Grey's Anatomy Star Says

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Long unhappy with Grey's Anatomy, cast members T.R. Knight and Katherine Heigl have both asked to be released from their contracts with the hit ABC drama, co-star James Pickens, Jr., reportedly says. While it has not gone down yet, it is only a question of when.

Or is it? Conflicting reports have had T.R. Knight asking to be let go for months now, but he hasn't budged. Meanwhile, Heigl's character, Izzie Stevens, has been the subject of more rumors than we can even count - most of which involve ghost-loving Izzie getting killed off.

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Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

Mark: Don't make me choose between you are her.
Lexie: Why? Because you'll choose her?
Mark: Yeah. I'll choose her.
Lexie: I think our relationship just ended.